Cast principale
Frank Welker
Scooby-Doo / Fred Jones / Self
Matthew Lillard
Norville 'Shaggy' Rogers / Self - Voice of "Shaggy"
Grey DeLisle
Daphne Blake / Self - Voice of "Daphne"
Kate Micucci
Velma Dinkley / Self - Voice of "Velma"
Janel Parrish
Janel Parrish - Host
Jerry Beck
Self - Animation Historian and Author
David Silverman
Self - Director and Producer, "The Simpsons"
Seth Green
Self - Actor, "Scooby-Doo 2: Monsters Unleashed"